Liquid Paraffin

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  • Liquid Paraffin
  • Liquid Paraffin

    Pre-washed and rigorously tested for ART procedures

    Liquid Paraffin by ORIGIO is a high-quality, pharmaceutical-grade, light liquid paraffin oil that has been widely used in ART for many years.

    The CooperSurgical fertility companies are the only supplier of Liquid Paraffin to test their oil products using Atomic Fingerprinting, a comprehensive method to quantitatively analyze the physicochemical properties of an oil using a combination of several techniques, including Fourier Transform Infrared Spectroscopy (FTIR), Nuclear Magnetic Resonance Spectroscopy (NMR), Gas Chromatography coupled with Flame Ionization Detection (GC-FID), and Kinematic Viscosity methods. This test provides quantitative molecular information on Liquid Paraffin.

    To ensure a high-quality product documented for embryo culture, Liquid Paraffin is extensively tested for peroxide values, sterility, endotoxin level (< 0.1 EU/mL) and 1-cell extended Mouse Embryo Assay (MEA). Liquid Paraffin by ORIGIO is pre-washed with HSA-containing media to remove any Potential lipophilic and hydrophilic endotoxins¹.

    Download our white paper “ORIGIO Liquid Paraffin and SAGE Oil for Tissue Culture: A rigorous assessment process for quality control” By Steve Fleming PhD, Our Director of Embryology

    Availability

    This product is available for sale in Europe, the U.S.A, Canada and Australia as well as selected countries in the rest of the world.
    Please always contact your local ORIGIO representative to confirm local availability.

    • Sterile filtered light paraffin oil of pharmacopoeia grade
    • Recommended storage in the dark² at 2-8°C³
    • Shelf life is 52 weeks after date of manufacturing
    • Shelf life after opening is 28 days
    Reference Description Size Shelf Life Guarantee*
    10100060 Liquid Paraffin 60 ml Minimum 16 weeks
    10105060 Liquid Paraffin 5×60 ml Minimum 16 weeks
    10100500 Liquid Paraffin 500 ml Minimum 16 weeks

    *Minimum time to expiry (from date of shipment from Denmark)

    Liquid Paraffin, Ph. Eur., which has been pre-washed with Universal IVF Medium.

    • Sterility tested (Ph. Eur., USP)
    • Endotoxin tested ≤ 0.1 EU/ml (Ph. Eur., USP)
    • Mouse Embryo Assay (MEA)

    1. Morbeck, DE et al. (2010) Washing mineral oil reduces contaminants and embryotoxicity. Fertil Steril 94: 2747-2752.
    2. Otsuki, J et al. (2007) Peroxidation of mineral oil used in droplet culture is detrimental to fertilization and embryo development. Fertil Steril 88: 741-743.
    3. Otsuki, J et al. (2009) Damage of embryo development caused by peroxidized mineral oil and its association with albumin in culture. Fertil Steril 91: 1745-1749.

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