Advanced Biopsy and Genetics Course

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Course Objectives

This three-day workshop aims to provide a comprehensive overview of the genetics services used in ART, whether for PGD of single gene defects or PGS as a screening tool for embryo selection, together with the procedures used in embryo biopsy and handling of biopsied cells.  The workshop will compare and evaluate the different stages: polar body biopsy, cleavage stage biopsy and trophectoderm biopsy.

Methods for each biopsy, including pipettes, media and possible uses of the biopsied material will be discussed.  Hands-on sessions will allow participants to practise each type of biopsy using mouse and/or hamster embryos.

The workshop is intended to provide participants with the core knowledge and introductory practical skills under the supervision of experienced practitioners.

It is not intended to be a complete training programme to attain full clinical competence – participants are urged to complete a logbook of in-house training using supernumerary or abnormally fertilised oocytes/embryos donated for training or research. 

Program

1  Current status of genetic analysis for ART

  • Genetics 101 – an introduction to genetics for non-geneticists;
  • PGD – analysis of sex-linked and single gene defects;
  • PGS/aneuploidy screening – comparison of methods and clinical data;
  • Controversies and future directions – dealing with difficult clinical issues and how is the technology developing?

Aims

This section gives an introduction to genetic testing and an overview of the technology and clinical data relating to genetic testing of biopsied material from oocytes and embryos.  Historical data and evaluation of newest testing methodologies will be presented, such that participants should have a sound basic appreciation of the potential benefits and limitations of these techniques.  In addition, discussions will look at the controversial parts of genetic testing such as dealing with mosaicism, addressing the issue of whether we discard potentially viable embryos , and how the developing technology might impact clinical practice.

2  Polar body biopsy

  • patients and aetiologies – which patients may benefit and which will not;
  • practical considerations – timings, media, techniques.

3  Cleavage stage biopsy

  • patients and aetiologies – which patients may benefit and which will not;
  • practical considerations – timings, media, techniques.

4  Trophectoderm biopsy

  • patients and aetiologies – which patients may benefit and which will not;
  • practical considerations – timings, media, techniques.

Aims

These sections specifically address the practical issues for each type of biopsy, with the intention of giving participants a sound grasp of the core skills.  In these sections, participants will learn primarily about techniques, media and consumables used and given an introduction to how biopsies are managed in the clinical setting.

5  Hands-on sessions

  • polar body biopsy;
  • cleavage stage biopsy;
  • trophectoderm biopsy.

Aims

These sections specifically address the practical issues for each type of biopsy, with the intention of giving participants a sound grasp of the core skills.  In these sections, participants will learn primarily about techniques, media and consumables used and given an introduction to how biopsies are managed in the clinical setting.

Minimum Experience

It is ESSENTIAL that all participants be experienced ICSI practitioners with suitably advanced micromanipulation skills and expertise; please note that the sessions will use Research Instruments Integra micromanipulators and Saturn laser systems.

Fee

Course fee is EUR 750. Transportation and accommodation are not included. Local transportation will be arranged. Lunch and refreshments will be provided during the course.

Registration

To register contact your ORIGIO Account Manager, find our partners here, or mail us at traininglabdk@origio.com

When

Find the full yearly schedule on this page.

2018-05-09T14:29:42+00:00 December 7th, 2017|
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