EZ-Range™ Pipettors and Tips

The EZ-Range is an innovative range of options for denudation and handling and includes:

  • EZ-Tip™ – Premium, plastic-tip pipette for denudation and handling. Read more here
  • EZ-Grip™ – Adjustable pipettor with easy and quick tip assembly
  • EZ-Squeeze™ Handle – Time-saving bulb and pipette denudation and handling system
  • EZ-Strip™ – A complete sterile single-use unit designed for exacting laboratory sterility standards
  • EZ-Stand™ – Helping keep your tools in place

The EZ-Range of denudation and handling devices is mouse embryo assay (MEA) and limulus amoebocyte lysate (LAL) tested and made from flexible and shatter-proof medical-grade plastic, designed to avoid scratching Petri dishes (as fragile glass pipettes are prone to do).

All products are rigorously checked for quality, ensuring consistent geometries, close tolerances, and smooth edges, and are sterilized in compliance with ISO 11137 standard for gamma irradiation.

Good to know

The use of EZ-Tips, EZ-Strips or EZ-Squeeze tips for denudation of the oocyte helps to minimize the duration of exposure to additional chemicals such as the hyaluronidase enzyme.1,2

The use of the EZ-Tips, EZ-Strips or EZ-squeeze tips may help facilitate improved fertilization rates by aiding the mechanical removal of the cumulus-corona radiata complex from around the oocyte, improving oocyte visibility for the user, and allowing injection of spermatozoa during ICSI procedures without the cumulus cells blocking the ICSI needle.1,2

Availability – This product is available for sale in selected countries worldwide.

Key Product Information

General questions about the EZ-Range™ portfolio

The EZ-Range portfolio includes both traditional pipetting (EZ-Grip, EZ-Tip), bulb pipetting (EZ-Squeeze) and a complete sterile single-use unit (EZ-Strip) to fulfill most ART laboratories’ demands.

EZ-Grip has a blow-out capacity to remove the remaining liquid in the tip, which can reduce the risk of oocytes and embryos getting stuck in the pipette tip.

EZ-Squeeze and EZ-Strip are both bulb pipettors with a closed tip system, and EZ-Strip additionally is a complete sterile single-use unit, which reduces the risk of cross-contamination between patient samples, for example high viral impact patients.

Tip vials and blister packs are color marked which will reduce the risk of using a tip diameter which is too small for the purpose, posing mechanical stress to the oocyte or embryo.

EZ-Range is designed for denudation of oocytes in preparation for ICSI and IVF techniques.

The EZ-Range devices can also be used for handling or moving oocytes and embryos from one container to another, for example between drops in a dish, between dishes or moving to a vitrification carrier.

The devices are also approved to handle biopsied material for PGT, such as polar bodies, blastomeres and trophectoderm cells.

EZ-Tip®

Premium Denudation and Transfer Pipette

EZ-Tip is a premium quality plastic tip for oocyte denudation or oocyte and embryo handling.

Our close-tolerance plastic tips are flexible, with smooth edges and consistent geometries.

The EZ-Tip can be easily extracted from its packaging and loaded into the pipettor.

The 0.9mm outside diameter fits the EZ-Grip and is compatible with all popular denudation and transfer pipettors.

“We have been using the EZ-Tip now for over a year. We have found them to be comfortable and easy to use whilst providing the fine control required for the safe handling of oocytes and embryos. The different diameters are well suited to all the stages of the IVF/ICSI process, from oocyte denudation to blastocyst transfer. ”

Marta Jansa Perez, Head of Embryology, IVF Hammersmith, UK

Key Features

High Quality

Consistent geometries and smooth edges

Quick Identification

Colour coded sizes

Compatible

Fits with EZ-Grip® and all popular denudation and transfer pipettors

Flexible

Unbreakable medical grade plastic tip that will not scratch Petri dishes

Finished Product MEA Tested

Every sterility batch of finished consumables is tested by an independent laboratory using a 1-cell stage mouse embryo toxicity test.

Finished Product LAL Tested

Each sterility batch of finished product is tested for bacterial endotoxins

Sterilised

Products are sterilised by an approved gamma irradiation facility meeting ISO 11137 standards

The pipette is made of medical-grade plastic which will flex and not damage the Petri dish.

EZ-Tips are compatible with commonly used denudation pipettors with a 0.9mm outer diameter.

EZ-Grip® Pipettor

  • Easy and quick tip assembly: simply push the tip onto the plunger wire – no need to unscrew the collet
  • Straightforward ergonomic design – comfortable to use for long periods
  • Smooth plunger for precise control
  • Requires minimal maintenance
  • Cleanliness: The equipment can undergo ultrasonic cleaning and be sterilized using an autoclave
  • Blow-out capacity to remove the remaining liquid in the tip

Tip size indicator
Manual indicator dial may be used as a reminder of the size of the EZ-Tip fitted (or left blank if preferred)
This can be beneficial during oocyte denudation when multiple size diameters might be used

Volume adjustment
Adjust the volume according to the procedural need, for example large volumes for oocyte denudation and small volumes for vitrification or tubing of cells. One turn equates to approximately 0.2 µL.

Comfort Grip (optional)
Ergonomic accessory which helps reduce the strain caused by repetitive pipetting and enables pipette free standing.

Cleanliness

The equipment can undergo ultrasonic cleaning and be sterilized using an autoclave

Quick and easy tip assembly

Simply push the tip onto the plunger wire – no need to unscrew the collet

Straightforward ergonomic design

Comfortable to use for long periods

Maintenance made easy

If a pipettor is not properly maintained, it may create workflow disruptions and frustration.

With our maintenance video the process of caring for your EZ-Grip device is simplified, making maintenance straightforward and accessible for all users. You can also read this in the Instructions for Use provided with the product.

The EZ-Grip may eventually require a replacement plunger wire and seals after extended use. These can be ordered as separate repair kits. One set is supplied with the unit.

You can find an instructional video on how to perform this replacement here and when visiting the EZ-Range product page.

Supplied with the EZ-Grip is a M2.5 hex key tool that is needed to loosen and replace the plunger wire. No tools are required to replace the seals.

EZ-Squeeze Pipette

EZ-Squeeze™ Tips

  • Save time – pre-assembled with bulb for faster set-up, ensuring a reliable seal
  • Individually packed for sterility
  • Shelf life of five years
  • Color coded – for easy identification

EZ-Squeeze™ Handle

Designed to offer precision aspiration and ease of handling
Designed for a comfortable working position, allowing the hand to rest on the working surface

Save time – pre-assembled with bulb for faster set-up, ensuring a reliable sea.

Designed for a comfortable working position, allowing the hand to rest on the working surface

Shelf life of 5 years for the tips

It is compatible with handles with a 4mm inner diameter for the bulb.

EZ-Strip® Pipette

EZ-Strip is a unique design, developed for maintaining the most exacting laboratory sterility standards. The EZ-Strip is a complete sterile unit for denudation and handling which reduces the risk of cross contamination.1 Systems using reusable devices or handles cannot make the same guarantees.

  • One complete sterile unit – designed as a pipettor handle and pipette in one to reduce the risk of cross-contamination between patient samples
  • Bulb pipetting – for precise volume control
  • Color-coded – for easy identification
  • Test tube lid forms the pipettor handle. The lid can be used to close the unit again after use
  • Designed for a comfortable working position, allowing the hand to rest on the working surface

One complete unit – reduces risk of cross-contamination between patient samples.

Designed for a comfortable working position, allowing the hand to rest on the working surface.

Test tube lid forms the pipettor handle. The lid can be used to close the unit again after use.

As a single-use system, EZ-Strip™ minimizes the risk of cross-contamination which is of paramount importance in assisted reproduction.

Clinics may consider that the benefits of minimizing the risk of cross-contamination outweigh the environmental concerns of additional packaging of a single-use item.

The pipette tip is made of medical-grade plastic which will flex and not damage the Petri dish.

Once a multipack is opened the sterility of each unit is compromised. With individual packaging, the sterility of each EZ-Strip is maintained.

Order Codes

Nominal Size Usage Color Product Code for 1 x vial (20 pipettes) Product Code for 5 x vial of 20 code(100 pipettes) Product Code for Individually Packed Tips(20 pipettes)
75µm Handling

Purple

7-72-2075/1 7-72-2075/5 7-72-4075/20
125µm Denudation

Blue

7-72-2125/1 7-72-2125/5 7-72-4125/20
135µm Denudation

Yellow

7-72-2135/1 7-72-2135/5 7-72-4135/20
145µm Denudation

White

7-72-2145/1 7-72-2145/5 7-72-4145/20
155µm Denudation

Green

7-72-2155/1 7-72-2155/5 7-72-4155/20
170µm Denudation

Red

7-72-2170/1 7-72-2170/5 7-72-4170/20
200µm Handling

Orange

7-72-2200/1 7-72-2200/5 7-72-4200/20
250µm Handling

Aqua

7-72-2250/1 7-72-2250/5 N/A
290µm Handling

Black

7-72-2290/1 7-72-2290/5 7-72-4290/20
600µm Handling

Brown

7-72-2600/1 7-72-2600/5 7-72-4600/20
Order Code Product
7-72-2800 EZ-Grip® without Comfort Rest
7-72-2802 EZ-Grip® with Comfort Rest
5-72-2000 EZ-Grip® Spares Kit (1x replacement seals / 1x M2.5 hexagon key / 1x plunger wire)
6-72-2810 EZ-Range Stand
Nominal Size Usage Color Product Code for 20 Individually Packed Tips with Bulb Pre-assembled
131µm Denudation

Blue

7-72-3131/20
135µm Denudation

Yellow

7-72-3135/20
145µm Denudation

White

7-72-3145/20
145µm Long Handling in tubes

White

7-72-3145L/20
155µm Denudation

Green

7-72-3155/20
170µm Denudation

Red

7-72-3170/20
200µm Handling

Orange

7-72-3200/20
290µm Handling

Black

7-72-3290/20
600µm Handling

Brown

7-72-3600/20
Nominal Size Usage Color Product Code for 20 Individually Packed EZ-Strip
131µm Denudation

Blue

7-72-1131/20
135µm Denudation

Yellow

7-72-1135/20
145µm Denudation

White

7-72-1145/20
145µm Long Handling in tubes

White

7-72-1145L/20
155µm Denudation

Green

7-72-1155/20
170µm Denudation

Red

7-72-1170/20
200µm Handling

Orange

7-72-1200/20
290µm Handling

Black

7-72-1290/20
600µm Handling

Brown

7-72-1600/20

Documents

EZ-Grip Specifications

Sample Delivery 0.2µl-3µl
Pipette Outer Diameter 0.9mm
Function Actuator to use with EZ-Tip® or plastic pipette tips with an 0.9mm outer diameter
Blow Out Utility Yes
Overall Dimensions 127mm length x 18mm diameter at widest point
Material Aluminium and Stainless Steel
Weight 36g
Sterilisation Method Autoclavable
Q. What is the pipette made of?
A. The pipette is made of medical grade plastic, which will flex and not damage the Petri dish.

Q. Will it fit my handle/pipettor?
A. We have tested EZ-Tip® with the commonly-used denudation pipettors with a 0.9 outer diameter. EZ-Tip® is intended as a high quality replacement for other brands.

Q. What size of pipette tips fit to my EZ-Grip®?
A. EZ-Tip® pipette tips and all popular pipette tips with a 0.9mm outer diameter.

Q. Does my EZ-Grip® require regular maintenance?
A. The EZ-Grip® may eventually require a replacement plunger wire and ‘O’ rings after extended use. These can be ordered from RI. One set is supplied with the unit.

Q. Do I need any tools to maintain my EZ-Grip®?
A. Supplied with the EZ-Grip®is a M2.5 hex key tool that is needed to loosen and replace the plunger wire. No tools are required to replace the seal.

Q. Does the EZ-Grip® need regular servicing?
A. We believe we use higher quality component parts to minimise maintenance requirements.

Q. Is the EZ-Squeeze™ bulb pipette compatible with competitor handles?
A. It is compatible with handles with a 4mm inner diameter. However, a EZ-Squeeze™ handle is supplied as required.

Q. Is the EZ-Squeeze™ handle compatible with competitor pipettes?
A. It is compatible with pipettes with a 1.5mm outer diameter with a bulb with a 4mm outer diameter.

Q. Why is it designed as single-use?
A. As a single-use system, EZ-Strip® minimises the risk of cross-contamination, which is of paramount importance in assisted reproduction.

Q. Is this wasteful?
A. RI has an environmental policy and it limits waste as much as possible. Clinics may consider that the benefits of minimising the risk of cross-contamination outweigh environmental concerns of additional packaging of a single-use item.

Q. What is the tip made of?
A. The pipette is made of medical grade plastic, which will flex and not damage the Petri dish.

Q. Why is EZ-Strip® individually packaged?
A. Once a multipack is opened the sterility of each unit is compromised. With individual packaging, the sterility of each EZ-Strip® is guaranteed.

  1. Data on file.
  2. Naji, O., Moska, N., Dajani, Y., El-Shirif, A., El-Ashkar, H., Hosni, M.M., Khalil, M., Khalaf, Y., Bolton, V. and El-Toukhy, T., 2018. Early oocyte denudation does not compromise ICSI cycle outcome: a large retrospective cohort study. Reproductive biomedicine online37(1), pp.18-24.